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Updated: Jul 15, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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Published on: June 6, 2025

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D1R-5-HT2AR解通过HDAC信号来减少抑郁行为

Weifen Li1,2, Tahir Ali1,3, Shengnan Mou1

  • 1State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
|October 2, 2023
PubMed
概括

研究人员在抑郁症中发现了一种新的多巴胺 (D1R) 和血清素 (5-HT2AR) 受体相互作用. 通过HDAC途径破坏这个复合体,用一种降低了通过HDAC途径的抑郁症状,提供了一个新的治疗点.

关键词:
这是一种5-HT2AR.这就是为什么BDNF是BDNF.D1RR 在线播放抑郁症 抑郁症 抑郁症在HDAC的基础上,HDAC是

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