自闭症谱系障碍从幼儿到学龄的持续性
Elizabeth Harstad1, Ellen Hanson1, Stephanie J Brewster1,2
1Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts.
JAMA pediatrics
|October 2, 2023
概括
许多被诊断患有自闭症谱系障碍 (ASD) 的幼儿在儿童时期晚些时候可能不符合标准. 较高的基线适应能力和女性性别与非持久的自闭症诊断有关.
科学领域:
- 发展心理学是发展心理学.
- 儿科神经学 儿科神经学
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 的患病率正在上升,强调早期诊断.
- 根据当前的诊断标准,在儿童早期被诊断出ASD的儿童的长期结果存在有限的数据.
研究的目的:
- 评估自闭症谱系障碍 (ASD) 诊断在最初被诊断为12至36个月龄的儿童中的持续性.
- 确定基线特征和干预措施是否影响ASD诊断持续到5至7岁.
主要方法:
- 一项自然历史队列研究跟踪了最初被诊断为ASD的儿童.
- 研究诊断评估是在5至7岁时使用DSM-5标准进行的.
- 评估包括自闭症诊断观察时间表-2,自闭症诊断访谈研究和认知措施.
主要成果:
- 在最初被诊断为ASD的213名儿童中,37.1%的儿童在5至7岁时不符合ASD标准 (非持续的ASD).
- 患有非持久性自闭症儿童的智商至少为70.
- 较高的基线适应能力和女性性别与持久性ASD诊断的可能性较低有关.
结论:
- 早期儿童自闭症谱系障碍 (ASD) 诊断并不总是持久的.
- 基线适应性功能和性别是ASD持续性的潜在预测因素.
- 这些发现凸显了幼儿时期自闭症诊断的动态性质.
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