在多发性硬化症中对上肢功能的评估:数字咬测试的可行性
Jennifer S Graves1, Marcin Elantkowski2, Yan-Ping Zhang2
1Department of Neurosciences, University of California, San Diego, CA, United States.
JMIR formative research
|October 2, 2023
概括
刺测试有效地评估多发性硬化症 (MS) 患者的上肢功能. 这种基于智能手机的工具提供客观,细粒度的数据,补充了MS管理的传统临床评估.
科学领域:
- 神经学 神经学
- 数字健康数字健康
- 康复医学 康复医学 康复医学
背景情况:
- 基于触摸屏的评估为患有多发性硬化症 (MS) 的人提供了方便的定量评估.
- 刺测试是Floodlight智能手机应用程序的一部分,旨在测量MS患者的上肢功能.
- 远程评估工具对于持续监测和管理MS等慢性疾病至关重要.
研究的目的:
- 评估刺测试作为一种可靠的工具,用于MS患者的远程上肢功能评估.
- 为了确定测试重复测试的可靠性,有效性和区分多发性硬化症患者群体的能力.
- 探索,基于IMU和疲劳性特征的实用性.
主要方法:
- 利用了Floodlight概念验证应用程序24周可行性研究的数据.
- 检查了13种捏,11种基于IMU的,以及13种疲劳特征.
- 评估可靠性 (ICC[2,1]),与临床措施的相关性 (斯皮尔曼),以及已知组的有效性.
主要成果:
- 扣扣特征显示出良好的可靠性 (ICC=0.54-0.81) 并与标准MS评估 (9HPT,EDSS,MSIS-29) 相相关.
- 疲劳性特征也与临床测量有显著的相关性.
- 基于IMU的特征具有类似的可靠性,但与临床评估的相关性较弱.
结论:
- 捏刺测试提供了一个远程,客观,和颗粒状的评估上肢功能在MS患者.
- 这个数字工具有可能补充MS的标准临床评估.
- 需要在更先进的多发性硬化症患者群体中进一步验证.
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