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喉颗粒细胞瘤:一个系统的审查

Alex S Luke¹, Theresa M Mairson², Inna A Husain³

¹Department of Otolaryngology-Head and Neck Surgery, Brooke Army Medical Center, Houston, Texas, USA.

The Laryngoscope

|October 2, 2023

概括

喉颗粒细胞瘤 (GCTs) 通常是良性的,但可以被误认为是癌症. 适当的诊断和管理,通常是简单的切除,防止对这些罕见的喉瘤进行不必要的侵略性治疗.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
头部和部手术头部和部手术
病理学病理学病理学

背景情况:

喉颗粒细胞瘤 (GCTs) 是一种罕见的瘤.
这些病变可以在组织病理学上模仿恶性瘤,导致诊断挑战.
错误分类可能导致过度治疗和显著的患者发病率.

研究的目的:

审查成年人的喉GCT病例.
突出诊断区别和管理策略.
为了证明错误分类对治疗升级的影响.

主要方法:

在PubMed,Ovid和EBSCO进行了系统的文献搜索.
包括到2021年12月发表的研究.
分析的重点是患者的表现,管理,病理和结果.

主要成果:

从87篇文章中确定了200名患有喉GCT的成年患者.
听力障碍 (85.9%) 和声/呼吸障碍 (14.1%) 是最常见的症状.
伪表皮瘤性增生 (PEH) 发生在33.5%,恶性瘤发生在2%,误诊发生在11%的病例中. 过度治疗发生在13.5%的良性病例中.

结论:

喉GCTs通常是良性的,并且可以通过初级手术切除来控制.
准确的组织病理学诊断至关重要,以避免不必要的激进疗法.
大多数GCT通过保守的外科手术方法解决,复发率低.

关键词:

空气通道的空气通道.颗粒细胞瘤是颗粒细胞瘤.喉科病理学喉科病理学喉 (Larynx) 是一个喉.吞下吞下吞下吞下吞下系统性审查系统性审查一个声音,一个声音,一个声音.

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