全球纵向菌株的使用,以检测左心室功能的亚临床减少
Ibtesam I El-Dosouky1, Eman H Seddik, Shaimaa Wageeh
1From the Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Critical pathways in cardiology
|October 2, 2023
概括
全球纵向应变 (GLS) 可以识别左心室 (LV) 功能受损,以低中风体积指数 (SVI) 和心脏输出指数 (COP) 表示,在患有保留射出分数 (EF) 的患者中. 这种评估对于在心力衰竭 (HF) 发展之前的早期检测至关重要.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏生理学 心脏生理学
背景情况:
- 左心室喷射分数 (LVEF) 可能不会准确地反映一些患有保留EF的患者的缩功能.
- 在患有保存EF且没有心力衰竭 (HF) 的患者中,LV功能和全球纵向应变 (GLS) 之间的关系需要进一步阐明.
研究的目的:
- 为了确定LV GLS是否能够检测LV功能受损 (低SVI和COP) 在患有保存EF且没有临床HF的患者中.
- 评估LV GLS在这个患者群体中的临床实用性.
主要方法:
- 100名LVEF≥50%的参与者接受了心声回声评估,包括LVEF,SVI,COP和GLS.
- 参与者被分为正常GLS (>-18%) 和低GLS (<-18%) 组.
主要成果:
- 减少的LV GLS与较低的SVI和COP有显著的相关性.
- LV GLS与SVI (r=0.75) 和COP (r=0.66) 显示出强烈的正相关性.
- 特定的GLS截止值预测了低SVI和高灵敏度和特异性的COP,确定GLS是最好的独立预测器.
结论:
- 损伤的LV GLS与LV功能减少 (较低的COP和SVI) 相关,即使没有临床HF,也在患者中保持EF.
- 将GLS与SVI和COP评估一起纳入常规的LV功能评估,可以帮助早期识别受损的LV功能.
- 在老旧的心声回声仪设备缺乏GLS能力的情况下,GLS评估可能特别有价值,这有助于在症状出现之前早期检测潜在的HF.
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