当前情况和早期慢性胰腺炎诊断中的问题
Koichi Ito1, Yusuke Takasaki, Toshio Fujisawa
1From the Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Pancreas
|October 2, 2023
概括
早期诊断慢性胰腺炎 (ECP) 具有挑战性,其确诊率较低,特别是在非酒精性病例中. 胰腺疼痛病例显示,ECP的诊断率略高.
科学领域:
- 胃肠病学 胃肠病学
- 胰腺学 胰腺学
- 诊断医学 诊断医学
背景情况:
- 早期慢性胰腺炎 (ECP) 的概念于2009年推出,但其流行病学特征和诊断挑战在很大程度上仍未得到解决.
- 了解ECP的诊断环境对于及时干预和管理至关重要.
研究的目的:
- 这项研究旨在调查诊断挑战,并使用既定标准确认早期慢性胰腺炎 (ECP) 的诊断率.
- 这项研究旨在评估当前诊断标准在不同患者队列中识别ECP的有效性.
主要方法:
- 在2019年4月至2021年11月期间,共分析了2502例病例.
- 早期慢性胰腺炎 (ECP) 诊断是使用2019年慢性胰腺炎临床诊断标准对4个不同的队列进行的,包括腹痛,胰腺酶异常,疑似ECP和接受内镜超声波的患者.
- 在150个选定的病例中使用内镜超声波来评估ECP发现.
主要成果:
- 在150例内镜超声波检查中怀疑ECP发现的病例中,只有14例 (9.3%) 得到证实.
- 对于ECP的确认率在酒精病例中为22.5%,在非酒精病例中为4.5%.
- 在四个队列中,诊断产量差异很大,从15%到0.13%,在腹部/背部疼痛队列中观察到的最高率 (48%的疼痛患者).
结论:
- 早期慢性胰腺炎 (ECP) 的整体诊断率很低,特别是在非酒精饮酒者中.
- 在患有胰腺疼痛的患者中,ECP诊断略有成功.
- 需要进一步的研究来完善和建立早期慢性胰腺炎 (ECP) 的更有效的诊断标准.
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