舒尤液通过减轻运动诱导的免疫功能障碍,表现出抗疲劳的特性
Shujing Zhang1, Yuemeng Sun1, Jiarou Wang1
1School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Journal of ethnopharmacology
|October 2, 2023
概括
舒尤 (SYD) 通过减少炎症和增强免疫反应来减轻运动引起的疲劳 (EF). 这种传统的中医药提高了身体的耐力,并调节了老鼠的关键免疫标志物.
科学领域:
- 传统中国医药 传统中国医药
- 运动生理学 运动生理学
- 免疫学 免疫学 免疫学
背景情况:
- (Shuyu) (SYD) 是一种传统的中医药,用于与缺乏相关的疾病.
- 运动引起的疲劳 (EF) 被认为是TCM的一个缺陷状况.
- SYD对EF和免疫功能障碍的药理学机制尚不清楚.
研究的目的:
- 为了评估SYD的抗疲劳作用.
- 调查SYD对运动诱导的免疫功能障碍的影响.
主要方法:
- 大鼠接受了跑步机训练,并接受了SYD的治疗.
- 分析了生物化学指标,炎症性细胞因子 (IL-6,IL-1β,TNF-α,IL-17,IL-10) 和免疫细胞群 (CD3+,CD4+,CD8+).
- 脏组织组织病理学被检查使用Hematoxylin和eosin (H&E) 染色.
主要成果:
- SYD治疗改善了体力,由增加的拉力和TTE/COR比率表明.
- SYD减少了疲劳的标记物,如乳酸 (LAC),血液尿素 (BUN) 和肌酸酶 (CK).
- SYD调节了炎症性细胞因子,降低了IL-6,IL-1β,TNF-α和IL-17,同时增加了IL-10,并增强了CD3+,CD4+和CD8+T细胞表达.
结论:
- 通过减轻炎症和增强免疫功能,SYD表现出抗疲劳的特性.
- SYD治疗对脏组织结构和免疫细胞平衡产生积极影响.
- 需要进一步的研究来阐明炎症因素和SYD调节的免疫反应之间的复杂关系.
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