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对中枢神经系统疾病的随机对照试验中的阳性和阴性细胞疗法

Di Chen¹, Hongyun Huang¹, Hooshang Saberi²

¹Beijing Hongtianji Neuroscience Academy, Beijing, P.R. China.

International review of neurobiology

|October 2, 2023

概括

随机试验显示,大多数细胞疗法在治疗中枢神经系统疾病方面的成功有限. 嗅觉吸收细胞对慢性缺血性中风有前途,需要进一步调查.

科学领域:

神经科学是一个神经科学.
再生医学是一种再生医学.
临床试验临床试验

背景情况:

二十多年来,人们一直在探索细胞疗法来治疗神经系统疾病,但有效性的确切证据仍然难以捉摸.
非随机化研究往往缺乏确定哪些细胞类型真正改善患者生活质量所需的可靠数据.

结论:

对于细胞疗法,建议进行进一步的RCT,显示出积极的神经修复效应,以优化结果.
应避免在相同的疾病中重复使用类似的方法 (剂量,输送,时间) 的失败细胞疗法.
强烈反对对细胞类型进行非随机试验,以往的RCT结果为负,以防止浪费资源和误导性结论.

关键词:

脑性麻脑性麻是一种疾病.多发性硬化症强烈的建议神经修复细胞疗法的神经修复细胞疗法帕金森病是帕金森氏症的一种疾病.随机对照试验是随机对照试验.脊髓损伤导致的脊髓损伤一次性中风,中风.

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