在手术期间使用iStent与术后选择性激光膜整形在接受白内障手术的早期绿内障患者中:一项回顾性比较研究
K Martini1, S Baillif1, S Nahon-Esteve1
1Ophthalmology Department, University Hospital of Nice, 30, voie Romaine, 06000 Nice, France.
Journal francais d'ophtalmologie
|October 2, 2023
概括
术内iStent和术后选择性激光斜视造形术 (SLT) 均有效降低眼内压力 (IOP),并在接受白内障手术的早期绿内障患者中降低绿内障药物,显示出类似的安全性和有效性.
科学领域:
- 眼科医生 眼科 眼科
- 视光眼管理 视光眼管理
- 手术干预 手术干预
背景情况:
- 早期的玻璃眼瘤管理通常涉及降低眼内压力 (IOP) 的干预措施.
- 白内障手术为结合治疗青光眼的手术提供了一个机会.
- 将微侵袭性玻璃眼手术 (MIGS) 与激光疗法进行比较对于治疗选择至关重要.
研究的目的:
- 为了比较手术内iStent注射®的疗效和安全性与360度选择性激光形造形 (SLT) 在接受白内障手术的早期绿内障患者.
- 为了评估眼内压力 (IOP) 降低和 postoperatively IOP-降低药物的需要.
- 评估程序后6个月和12个月的结果.
主要方法:
- 这是一项涉及73只眼睛的回顾性非随机研究.
- 第1组:白内障手术使用手术内置的iStent (n=40).
- 第二组:白内障手术与术后SLT在一个月 (n=33).
- 主要终点:≥20%的IOP从基线下降到6个月.
- 二次终点: IOP 在1,6和12个月;药物使用在6和12个月.
主要成果:
- 基线IOP和人口统计数据在各组之间相似,尽管iStent组的基线药物使用率较高 (P=0.04).
- 在6个月后,51%的iStent患者和60%的SLT患者实现了≥20%的IOP降低 (P=0.431),表明类似的疗效.
- 在6个月和12个月的组之间没有观察到平均内血压降低药物的显著差异.
结论:
- 在手术期间的iStent和手术后的360°SLT在治疗白内障手术的早期绿内障患者的IOP和药物负担方面表现出相似的安全性和有效性.
- 在iStent和SLT之间进行选择时,应考虑外科医生的专业知识和成本效益.
- 无论是MIGS还是激光疗法都是联合白内障和绿内障手术的可行选择.
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