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Updated: Jul 15, 2025

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CHD8调节肠道上皮细胞功能,并通过肠-大脑轴影响与自闭症相关的行为

Ipsita Chatterjee1, Dmitriy Getselter1, Nasreen Ghanayem1

  • 1Azrieli Faculty of Medicine, Bar Ilan University, Safed, 13215, Israel.

Translational psychiatry
|October 2, 2023
PubMed
概括

染色体螺旋酶DNA结合蛋白 (CHD8) 突变会影响肠道功能,并可能导致自闭症行为. 在CHD8突变的小鼠中恢复肠道健康改善了社会行为,这表明肠道和自闭症之间存在联系.

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