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Updated: Jul 15, 2025

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UBE3B通过对抗HIF-2α降解来促进乳腺癌的进展

Yijie Wang1, Xiong Liu2, Min Wang1

  • 1Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Institute of Biomedical Science, College of Life Sciences, Shandong Normal University, Jinan, Shandong, 250014, China.

Oncogene
|October 2, 2023
PubMed
概括

E3酶UBE3B针对HIF-2α进行无处不在,抑制其降解并促进乳腺癌的生长. UBE3B上调与瘤中的HIF-2α相关,揭示了一种新的癌症机制.

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