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Xueyi Dong1,2, Mei R M Du3, Quentin Gouil3,4

  • 1The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. dong.x@wehi.edu.au.

Nature methods
|October 2, 2023
PubMed
概括

这项研究将长期阅读的RNA测序分析工具用于异构体检测和差异表达的基准. 在异形检测方面,StringTie2和bambu表现出色,而在差异表达分析方面,DESeq2,edgeR和limma-voom领先.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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