系统微循环在儿科紫外线炎中的参与
Carlyn V Kouwenberg1, Julia Spierings2, Evianne L de Groot3
1Department of Ophthalmology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands. C.V.Kouwenberg-3@umcutrecht.nl.
Pediatric rheumatology online journal
|October 2, 2023
概括
儿科内膜炎影响全身微循环,变化因亚型而异. 与对照组相比,指甲毛细管镜检查显示了毛细管密度和形态上的差异.
科学领域:
- 眼科医生 眼科 眼科
- 儿科风湿病学 儿科风湿病学
- 微循环研究 微循环研究
背景情况:
- 儿科卵膜炎是一种严重的眼睛疾病,导致视力丧失.
- 视网膜微循环受到中期和帕努韦炎的影响.
- 儿科内膜炎的全身微循环还没有得到充分的研究.
研究的目的:
- 为了研究患有紫外线炎的儿童的全身微循环.
- 为了比较儿科紫外炎患者和健康对照组的指甲毛细管镜检查 (NFC) 结果.
主要方法:
- 在119名患有非传染性脑膜炎的儿童和25名健康对照中进行了指甲毛囊镜检查 (NFC).
- 评估毛细血管密度,扩张毛细血管,无血管区域,微型出血和毛细血管形态.
- 对年龄和性别进行调整的回归分析,以比较NFC参数.
主要成果:
- 儿科紫外炎病例显示,毛细血管的扩张和分枝毛细血管比对照人群明显多.
- 介质性脑膜炎病例的毛细血管扩张更大.
- 之前的脑膜炎病例的毛细血管密度较低,毛细血管分支较多.
结论:
- 患有紫外线炎的儿童,即使没有全身性疾病,也会表现出改变的全身微循环.
- 通过NFC识别的微循环变化在儿科紫外炎亚型之间有所不同.
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