邻近的骨对形骨的影响在下重建中,带有骨自由板
Claudius Steffen1, Ana Prates Soares2,3, Thelma Heintzelmann2
1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Oral and Maxillofacial Surgery, Augustenburger Platz 1, 13353, Berlin, Germany. claudius.steffen@charite.de.
Head & face medicine
|October 2, 2023
概括
在下重建中,骨在分段间隙的起源不会显著影响骨结合. 机械和临床因素更为关键,以取得成功的外科手术结果在骨自由手术.
科学领域:
- 口腔和牙面部外科手术
- 再生医学是一种再生医学.
- 生物材料科学 生物材料科学
背景情况:
- 骨重建通常涉及骨自由板.
- 伪 (非工会) 发生率受到机械和形态因素的影响.
- 这项研究通过尽量减少机械混因素来分离骨源对骨结合的影响.
研究的目的:
- 在下重建中评估骨起源在骨间隙对骨结合的影响.
- 为了比较骨与骨之间的接口和骨与之间的接口.
- 为了确定骨非联合的风险因素.
主要方法:
- 对接受多段骨自由下重建的患者的回顾性分析.
- 使用患者特定的3D打印重建板进行骨质合成.
- 使用圆束计算断层扫描 (CBCT) 和组织学/微型CT评估跨段区的骨体积和宽度变化的定量分析.
主要成果:
- 区间间隙的骨源没有显著影响骨体积变化 (p=0.223).
- 放射治疗 (p<0.001),CBCT扫描之间的时间 (p=0.006) 和伤口愈合障碍 (p=0.005) 是非工会的独立风险因素.
- 初步的微观结构分析显示,骨-骨和骨-下骨之间没有形态差异.
结论:
- 在下重建中,分段间隙的骨接口类型不会显著影响长期骨愈合.
- 机械和临床因素似乎更为关键的下巴重建使用骨免费片的成功.
- 进一步研究机械和临床特性是有必要的.
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