相关实验视频
Updated: Jul 15, 2025

09:03
Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
15.9K
基于纳米在微粒的多功能系统作为药物输送策略:进展,挑战和未来的前景
Suzana Gonçalves Carvalho1, Aline Martins Dos Santos1, Amanda Letícia Polli Silvestre1
1Department of Drugs and Medicines, School of Pharmaceutical Sciences - São Paulo State University (UNESP), Araraquara, Brazil.
Expert opinion on drug delivery
|October 3, 2023
概括
纳米-在-微粒提供创新的药物向通过结合纳米粒子和微粒的战略. 这种方法通过克服各种疾病的生理障碍来个性化治疗.
科学领域:
- 制药技术 制药技术 制药技术
- 药物输送系统 药物输送系统
- 生物材料科学 生物材料科学
背景情况:
- 创新的药物输送系统对于向治疗至关重要.
- 纳米在微粒系统是个性化医学的有前途的战略.
- 这些系统旨在克服疾病治疗中的生理障碍.
研究的目的:
- 审查纳米-在-微系统,专注于生物材料,制备和应用.
- 讨论这些系统的生理学考虑,挑战和管理策略.
- 突出多功能纳米在微粒系统在制药技术中的新性.
主要方法:
- 关于纳米在微粒子系统的文献综述.
- 生物材料和制备技术的分析.
- 探索应用和临床翻译策略.
主要成果:
- 纳米在微粒系统允许特定和个性化的药物向.
- 各种生物材料和制备方法适合这些系统.
- 多功能纳米微粒在药物管理中具有独特的优势.
结论:
- 纳米在微粒系统是制药技术的重大进步.
- 对生物材料和多功能系统的进一步研究是有必要的.
- 这些系统有可能改善临床转化和治疗结果.
相关概念视频
Drug Delivery: Overview
314
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
314
Factors Affecting Dissolution: Particle Size and Effective Surface Area
876
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
876

