心肌功能成像标记物的预后价值在接受过导管大动脉置换的老年患者中
Alexandra Dadarlat-Pop1,2, Adrian Molnar3,4, Adela Serban1,2
1Cardiology Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.
通过导管的大动脉置换 (TAVR) 在老年患者中改善了左心室应变. 右心室菌株在TAVR后没有显著变化,表明TAVRR.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 医疗器械 医疗器械
背景情况:
- 过导管大动脉置换 (TAVR) 是老年人严重症状大动脉狭窄的主要治疗方法.
- 缺少已确立的左心室 (LV) 和右心室 (RV) 逆向重塑TAVR后的回声心脏学标志物.
- 了解TAVR后心室应变动态对于评估治疗结果至关重要.
研究的目的:
- 为了评估LV和RV菌株的变化,使用斑点跟踪回声心脏学.
- 在接受TAVR后三个月,评估老年患者的这些变化.
主要方法:
- 这项研究包括52名老年患者 (平均年龄77岁),他们接受了输血TAVR.
- 在基线和TAVR后3个月进行了心声评估,包括LV和RV应变和射出分数.
- 分析了应变参数,射出分数,年龄和NT-proBNP水平之间的相关性.
主要成果:
- 在TAVR3个月后 (p < 0.001) 观察到LV全球纵向菌株 (GLS) 的显著改善.
- 在3个月后,没有发现RV GLS的显著变化.
- LV 喷射分数有所改善,LV-GLS 与基线 LV-GLS,RV 菌株,LVEF 和 NT-proBNP 相相关.
结论:
- TAVR导致LV菌株的显著改善,表明有益的重塑.
- RV菌株没有显著的变化,突出了进一步研究的潜在领域.
- LV菌株参数是评估老年患者TAVR结果的有价值的心声回声标记.
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