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在接受非心脏手术的儿童中,术后认知功能障碍的预测因素和发生情况:前性队列研究

Fang-Fang Han^1,2, Xiu-Mei Wang², Hai-Jun Zhang^1,2

¹The First Clinical Medical College of Lanzhou University Lanzhou Gansu P.R. China.

|October 3, 2023

概括

手术后认知功能障碍 (POCD) 影响15.6%的非心脏手术后的儿童. 关键的风险因素包括先前的手术,更长的麻醉时间和早期的术后发烧,这凸显了儿童手术护理需要保持警的必要性.

科学领域:

儿科麻醉学儿科麻醉学
神经科学是一个神经科学.
外科手术的结果

背景情况:

术后认知功能障碍 (POCD) 在心脏手术后的儿童中被认可.
在接受非心脏手术的儿童中,POCD的发病率和风险因素在很大程度上是未知的.

研究的目的:

确定非心脏手术后儿童早期神经认知功能障碍的发病率.
为了确定与这种儿科患者群体中POCD发展相关的潜在风险因素.

主要方法:

一项前性观察性研究,涉及200名接受选择性非心脏手术的儿童 (4-14岁) 和100名年龄匹配的对照.
使用韦克斯勒尺度进行神经认知评估,进行了手术前和手术后3天.
多变量逻辑回归分析确定了POCD的独立风险因素.

主要成果:

早期POCD的整体发病率为15.6%.
确定POCD的独立风险因素包括手术史,更长的麻醉持续时间和早期术后发烧 (EPF).

结论:

早期的术后认知功能障碍发生在15.6%的非心脏手术后的儿童中.
曾经接受过手术,长期麻醉或EPF的儿童患POCD的风险增加.

关键词:

麻醉是一种麻醉.孩子们的孩子们的孩子们的孩子们.认知功能障碍认知功能障碍手术手术手术手术手术手术手术手术史的外科历史

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