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产后母亲护理可以缓和产前双暴露对后代神经发育,行为和转录学结果的影响

Samantha C Lauby^1,2, Hannah E Lapp¹, Melissa Salazar¹

¹Department of Psychology, College of Liberal Arts, University of Texas at Austin.

bioRxiv : the preprint server for biology

|October 3, 2023

概括

产前接触双 (BPs) 影响神经发育,但这种影响取决于母亲的照顾. 产后护理可以减轻高血压暴露的不良结果,影响成年人的行为.

科学领域:

环境健康环境健康
神经内分泌学神经内分泌学
发展性毒理学发展性毒理学

背景情况:

双 (BPs),包括BPA和类似物,是内分泌干扰剂,与不良的神经发育结果有关.
产前血压暴露可能会对母亲的护理产生负面影响,进一步影响后代的神经发育和行为.
有限的数据存在于非BPA双和产前BP暴露和母亲护理对成年人行为的综合影响.

结论:

产后母亲护理对于调解产前双暴露的神经发育和行为后果至关重要.
了解这些相互作用可能会揭示减轻环境化学物质暴露对健康的不利影响的策略.
雌激素受体信号传递和基因表达过程是关键的生物机制.

关键词:

类似焦虑的行为.注意力集的转移注意力集的转移双醇是一种双醇.雌激素受体信号传递孕产妇的护理孕产妇的护理神经发育的神经发育转录组 (transcriptome) 是一个转录组.

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