在全身麻醉下对吸烟患者的无痛胃镜和POCD进行研究
Wan-Qiu Yu1, Yu-Hang Zhu1, Xin-Xin Yang1
1Department of Anesthesiology Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China.
Ibrain
|October 3, 2023
概括
吸烟可能是早期术后认知功能障碍 (POCD) 的独立风险因素. 与非吸烟者相比,吸烟者在麻醉后的迷你精神状态检查得分明显较低.
科学领域:
- 麻醉学 麻醉学
- 神经外科 神经外科
- 公共卫生 公共卫生
背景情况:
- 越来越多的接受麻醉和手术的患者是吸烟者.
- 研究吸烟作为术后认知障碍的独立风险因素对于医学进步至关重要.
研究的目的:
- 确定吸烟是否是术后认知功能障碍 (POCD) 的独立风险因素.
主要方法:
- 一项双盲,并行,受控的研究对112名在全身麻醉下进行无痛胃镜检查的患者进行.
- 迷你精神状态检查 (MMSE) 评分在基线,麻醉后和麻醉后3天被评估.
- 使用后勤回归分析了不良事件.
主要成果:
- 与对照组相比,吸烟组在麻醉后立即有明显较低的MMSE得分 (p <0.05).
- 在麻醉后3天的组之间没有观察到MMSE得分的显著差异.
- 在吸烟组 (p < 0.05) 中,发现抽刺,术后咳和SpO2 < 90%的发病率增加.
- 逻辑回归表明吸烟与术后咳有关.
结论:
- 吸烟可能是早期术后认知功能障碍的独立风险因素.
- 吸烟与诸如术后咳等不良事件有关.
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