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由于耐卡巴因的医院获得的感染Providencia stuartii

Swati Sharma¹, Sangita Pramanik², Pooja Marndi²

¹Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

The Indian journal of medical research

|October 3, 2023

概括

耐卡巴胺的Providencia stuartii (CRPS) 导致与医疗相关的感染 (HAI),通常被忽视. 这项研究确定了CRPS作为一个重要的HAI代理,突出其耐药性和克隆传播,特别是在ICU.

科学领域:

传染性疾病传染性疾病
微生物学微生物学
抗微生物耐药性抗微生物耐药性

背景情况:

与医疗保健相关的感染 (HAI) 构成一个重大挑战,而抗卡巴胺生物体 (CRO) 是一个主要问题.
在一项回顾性调查中,发现了一种异常的HAI患病率,由抗卡巴因的Providencia stuartii (CRPS) 引起.

研究的目的:

调查与P. stuartii相关的HAI的发生情况.
为了描述CRPS分离体的耐药性概况.

主要方法:

对由CRPS引起的HAI病例的回顾性分析.
对扩展光谱β-乳酸酶,AmpC过度生成和抗卡巴胺耐药性的表型检测.
使用重复的外基巴林德罗姆聚合酶连锁反应 (REP-PCR) 进行分子类型化.

主要成果:

确定了8例CRPS HAI病例,包括呼吸器相关的肺炎,手术部位感染,导管相关的尿路感染和血液感染.
所有CRPS分离物都是AmpC高生产者和碳烯酶生产者,发现了blaNDM和blaIMP基因.
REP-PCR显示了携带blaNDM的分离物之间100%的相似性,表明了克隆相关性. 在ICU患者的部中注意到P. stuartii的高携带率.

结论:

慢性脊髓炎 (CRPS) 是一种重要的,但常常被忽视的HAI的原因.
这些发现凸显了医疗保健机构内CRPS的克隆传播潜力.
之前的胆固醇治疗和长时间住院与CRPS感染有关.

关键词:

这就是AmpCC.布拉 NDM 布拉 NDM 在线耐卡巴烯姆的P. 斯图尔蒂菌.科里斯 (Colistin) 是一个古老的城市.重症监护病房的重症监护病房是一个重症监护病房.

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