在口腔潜在恶性疾病和口腔恶性瘤中评估结晶模式:一项前性研究
A Jacob Prakash1, K Sai Surendra1, M Vijaya Lakshmi1
1Department of Oral and Maxillofacial Pathology, Lenora Institute of Dental Sciences, Andhra Pradesh, India.
Journal of cancer research and therapeutics
|October 3, 2023
概括
结晶测试显示了检测口腔恶性瘤和潜在恶性疾病的高灵敏度. 这种具有成本效益的血液测试为早期口腔癌查提供了一个有前途的新方法.
科学领域:
- 在瘤学瘤学.
- 诊断医学 诊断医学 诊断医学
背景情况:
- 口腔癌经常存在于晚期,导致50%的5年生存率.
- 早期发现口腔癌至关重要,因为它通常会通过癌前阶段发展.
- 结晶测试是一种未被充分利用,经济和简单的诊断技术,用于早期癌症检测.
研究的目的:
- 评估结晶试验的诊断潜力.
- 分析患有口腔恶性瘤,口腔潜在恶性疾病 (OPMDs) 和烟草使用者的结晶模式.
主要方法:
- 该研究涉及15名患有口腔恶性瘤,OPMD,烟草使用者和15名健康对照患者.
- 一滴血被用于结晶测试.
- 分析了水晶图案,以评估诊断的准确性.
主要成果:
- 结晶试验显示,口腔恶性瘤的灵敏度为93.3%,OPMDs的灵敏度为80.0%.
- 烟草使用者的敏感度为20.0%.
- 基平方分析表明,基于结晶模式,OPMD和口腔恶性瘤之间存在显著的关联 (P <0.05).
结论:
- 结晶试验是一种敏感,可靠,经济,并且对查OPMD和口腔恶性瘤具有最小侵入性的方法.
- 严格遵守物理条件对于准确的测试结果至关重要.
- 这种测试有可能提高口腔癌的早期检测率.
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