牙突变和异常学脊椎病之间的关系:通过对观察性研究的元分析进行系统性审查
Francisca Gámiz-Bermúdez1, Alfonso Javier Ibáñez-Vera2, Esteban Obrero-Gaitán2
1Unidad de Gestión Clínica Adra, Distrito Sanitario Poniente de Almería, Avenida Picasso, Adra, Spain.
异形脊椎病 (IS) 与显著的口腔神经变化有关,包括缺陷和部功能障碍. 患有缺陷闭塞的患者患上IS的患病率较高,这强调了IS患者需要进行口腔面部检查的必要性.
科学领域:
- 矯正牙科和牙科科學
- 整形外科和脊柱疾病
- 系统性审查和元分析
背景情况:
- 异形脊柱病 (IS) 是一种复杂的脊柱形,具有多因素的病因.
- 牙突变的改变,包括牙封闭和关节 (TMJ) 功能,代表了潜在的促成因素或并发症.
- 了解这些疾病之间的关系对于全面的患者管理至关重要.
研究的目的:
- 系统地审查和对观察性研究进行元分析,评估口腔突变和异常学脊椎病之间的关联.
- 在IS患者中量化特定的面部或面部疾病的患病率和影响.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,CINAHL) 使用相关的MeSH术语进行了系统的文献搜索.
- 进行了对14项涉及3018名受试者的精选观察性研究的元分析.
- 计算了患病率和标准化平均差异 (SMD) 的几率比率 (OR),以综合发现.
主要成果:
- 异形脊椎病 (IS) 与安格尔的II类缺陷 (OR = 2.052) 和交叉咬伤 (OR = 2.234) 有意义地相关.
- 患有缺陷闭塞的患者表现出显著更高的IS患病率 (OR = 4.633).
- 患有IS的个体呈现出增加的喷射 (SMD = 0.405) 和更大的关节障碍 (TMD) 功能障碍 (SMD = 1.153).
结论:
- 与对照人群相比,IS患者的闭塞障碍风险增加了一倍,部功能障碍和喷气明显增加.
- 缺陷关闭与IS患病率增加多达四倍有关.
- 对于被诊断患有异常学脊椎病的患者,建议进行常规的口腔面部检查,以识别和管理相关的口腔学变化.
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