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在最初的第一轮向活检之后,第二轮MRI向超声波导向融合前列腺活检的产量
Yashmin Nisha1, Shen Yi1, Rodney H Breau2
1Department of Medical Imaging, The Ottawa Hospital. The University of Ottawa, ON, Canada.
概括
第二轮MRI-US融合活检在约20%的病例中检测出临床显著的前列腺癌. PRECISE评分可以帮助识别需要重复活检以准确诊断前列腺癌的患者.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 前列腺癌 (PCa) 诊断通常需要重复活检.
- 磁共振成像-超声波 (MRI-US) 融合活检是向组织采样的一个关键工具.
研究的目的:
- 为了确定临床显著 (CS) 前列腺癌的第二轮MRI-US融合活检的诊断产量.
- 在重复活检中确定预测CS前列腺癌 (PCa) 诊断的因素.
主要方法:
- 在2013年至2021年期间,85名男性接受了92次第二轮MRI-US融合活组织检查.
- 收集的数据包括患者年龄,PSA,PSAD,病变特征 (大小,位置,ADC值,PI-RADS,PRECISE得分).
- 使用后勤回归比较数据与组织病理学诊断 (ISUP等级组≥2对CSPCa) 使用后勤回归.
主要成果:
- 第二轮活检诊断出CSPCa在25%的病变和21%的病变中具有最初负面的活检结果.
- 在PSA,病变大小,位置或PI-RADS得分方面,在CSPCa和非CSPCa之间没有发现显著差异.
- PSAD,ADC值和PRECISE得分显示出与CS PCa诊断的趋势或关联,PRECISE得分达到统计学意义 (p<0.01).
结论:
- 重复第二轮向的MRI-US融合活检在诊断CS PCa中有效,在很大一部分患者中有效.
- PRECISE评分显示,作为选择可能从第二轮活检中受益的患者的预测标记,它是有前途的.
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