概括
患有高血压和多种并发症的患者面临着药物坚持的挑战. 该研究发现,高风险并发症的数量与坚持水平之间存在不一致的关系.
科学领域:
- 临床药房 临床药房
- 医疗保健服务研究 医疗服务研究
- 慢性疾病管理 慢性疾病管理
背景情况:
- 高血压管理通常涉及多种药物由于高风险的并发症.
- 在患有高血压和并发症的患者中,多药可以增加药物坚持的负担.
- 慢性疾病的数量是影响药物坚持的潜在因素.
研究的目的:
- 基于药物服药的坚持,比较高血压和高风险并发症患者的特征.
- 调查高风险并发症数量与同时服用药物的坚持之间的关联.
- 在需要多种药物的患者中识别药物坚持的模式.
主要方法:
- 2018年韩国卫生小组调查的二次数据分析.
- 包括2230名患有高血压和至少一种高风险并发症的多种药物患者.
- 根据每种情况的药物坚持,根据使用多项逻辑回归分析的每种情况的药物坚持,将其分类为坚持,次优和不坚持的组.
主要成果:
- 附加,次优和非附加组分别包括85%,11%和4%的患者.
- 更多的高风险并发症与非最佳坚持组 (aOR=1.46) 与坚持组相关.
- 较少的高风险并发症与非附属组 (aOR=0.52) 与附属组相关.
结论:
- 确定了三个不同的同时服用药物的坚持群体.
- 高风险并发症数量与药物坚持群体之间的关联不一致.
- 需要进一步的研究,以了解这种患者群体中复杂的坚持模式.
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