前列腺癌超声波治疗的现状和未来前景
Sunao Shoji1, Jun Naruse2, Kazuya Oda2
1Department of Urology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. sunashoj@mail.goo.ne.jp.
Journal of medical ultrasonics (2001)
|October 3, 2023
概括
使用高强度聚焦超声波 (HIFU) 和高强度定向超声波 (HIDU) 的焦点疗法为局部性前列腺癌 (PC) 提供了最少侵入性的选择,可保持功能. 需要进一步的研究来确认这些先进的超声波治疗的瘤和功能结果.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 最少侵入性的手术
背景情况:
- 局部性前列腺癌 (PC) 的标准治疗方法,激进前列腺切除术和放射治疗,携带尿路,性功能障碍和严重并发症的重大风险.
- 磁共振成像 (MRI) 的最新进展使得临床显著PC (csPC) 的精确定位成为可能.
- 焦点治疗已经成为一种有希望的微创方法来治疗CSPC,同时保持关键的解剖结构.
研究的目的:
- 评估基于超声波的焦点治疗作为局部性前列腺癌 (PC) 的最小侵入性治疗的潜力.
- 为了比较高强度聚焦超声波 (HIFU) 和高强度定向超声波 (HIDU) 在PC治疗中的有效性和安全性.
- 确定需要进一步研究,以建立PC管理中超声疗法的标准化治疗方案.
主要方法:
- 对全腺和局部PC的焦点治疗中跨直肠HIFU的临床结果的综述.
- 对PC治疗中通过尿道HIDU的最近短期临床结果的分析.
- 考虑HIFU和HIDU的局限性,包括大前列腺和体积.
主要成果:
- 根据现有的临床数据,HIFU被认为是局部PC焦点治疗的有吸引力的选择.
- 在目前的局限性解决之前,HIDU显示出在PC治疗中广泛使用的潜力.
- 无论是HIFU还是HIDU,都需要适当的应用才能有效地治疗前列腺内的各种点区域.
结论:
- 基于超声波的焦点疗法,包括HIFU和HIDU,是局部PC的可行最小侵入性策略.
- 解决与前列腺大小和结相关的局限性对于优化治疗提供至关重要.
- 配对和历史控制的研究对于验证这些新型PC超声波治疗方法的瘤和功能结果至关重要.
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