患有贝塞特病的儿童心血管并发症的风险
Selcan Demir1, Ali Duzova2, Tevfik Karagoz3
1Department of Pediatric Rheumatology, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.
Rheumatology (Oxford, England)
|October 3, 2023
概括
评估了儿科贝塞特病 (BD) 患者的心血管风险. 虽然一些指标相似,但血管参与显示出潜在的大动脉硬,这表明对所有儿科BD患者进行全面的心血管评估至关重要.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 心血管医学 心血管医学
- 血管生物学 血管生物学
背景情况:
- 贝塞特病 (BD) 在儿科患者中可能导致显著的长期心血管疾病.
- 在儿科BD中评估心血管并发症风险至关重要,特别是区分患有和没有血管参与的患者.
- 传统的心血管风险因素被排除在外,以隔离BD特定的影响.
研究的目的:
- 评估儿科BD患者心血管并发症风险.
- 为了比较儿科BD患者的心血管风险标志物,有和没有血管干扰.
- 确定门诊血压监测 (ABPM) 在评估儿科BD心血管风险时的实用性.
主要方法:
- 包括31名符合2015年PEDBD标准的儿科BD患者.
- 使用了24小时的门诊血压监测 (ABPM),胸前心电回声和动脉内膜介质厚度 (cIMT) 测量.
- 排除了患有活跃疾病或其他已知的心血管风险因素的患者.
主要成果:
- 在31名儿科BD患者中,10名 (34.4%) 患有异常ABPM.
- 在患有和没有血管干扰的患者之间,没有发现ABPM参数或cIMT的显著差异.
- 心声图显示左心室外流通道速度和速度时间积在患有血管干扰的BD患者中增加,这表明潜在的主动脉硬.
结论:
- 患有血管干扰的儿科BD患者可能会出现心血管风险因素的增加.
- 建议对所有儿科BD患者进行综合性心血管评估,无论具体系统参与程度如何.
- 门诊血压监测 (ABPM) 对准确定义儿科BD的高血压和心血管风险显示出希望.
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