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Updated: Jul 15, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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TSC2 S1365A突变有效调节CD8+T细胞功能和分化,并改善采用细胞癌症治疗

Chirag H Patel1, Yi Dong1, Navid Koleini2

  • 1Bloomberg-Kimmel Institute for Immunotherapy.

JCI insight
|October 3, 2023
PubMed
概括

在CD8+ T细胞中调节TSC2酸化,增强了它们的效应器功能和记忆形成. 这一发现为设计更好的CAR-T细胞提供了一种新的策略,以有效地对抗癌症.

关键词:
适应性免疫是一种适应性免疫.癌症免疫疗法癌症免疫疗法细胞生物学 细胞生物学免疫学 免疫学 免疫学在T细胞,T细胞.

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