在接受全身麻醉的儿童中,出现妄想和大脑状态参数之间的关联:一项前性观察性研究
Weizhi Zhang1, Yansheng Cheng1, Li Zhang1
1Department of Anesthesiology, Shanxi Provincial Children's Hospital, Taiyuan, China.
Paediatric anaesthesia
|October 3, 2023
概括
在接受麻醉的儿童中,可以使用实时大脑状态参数预测出现妄想. 焦虑指数和舒适指数在识别这种常见的术后并发症方面表现有前途.
科学领域:
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
- 儿科医学 儿科医学
背景情况:
- 突发性妄想 (ED) 是一般麻醉后儿童经常出现的术后神经复杂症.
- 目前用于预测ED的方法有限,需要开发新的预测工具.
研究的目的:
- 评估实时大脑状态参数与儿科患者进行全身麻醉进行牙科手术时发生的ED之间的关联.
- 评估波纹指数,疼痛值指数,焦虑指数和ED舒适度指数的预测能力.
主要方法:
- 一项涉及116名儿童 (3-6岁) 在全身麻醉下接受牙科手术的研究.
- 电脑电图 (EEG) 数据记录在四个时间点:麻醉后给药,手术结束,输出管,以及对口头刺激的反应.
- 患者被评估ED使用小儿麻醉出现 Delirium (PAED) 尺度;接收器操作特征 (ROC) 曲线被用于分析预测值.
主要成果:
- 焦虑指数 (AUC [95% CI]:0.84 [0.75-0.93]) 和舒适指数 (AUC [95% CI:0.89 [0.81-0.96]) 与ED有显著的相关性.
- 勃起障碍的发生率为31.90%. 焦虑指数的最佳切线值为46.5 (灵敏度为73.0%,特异性为89.9%),舒适指数为68.5 (灵敏度为91.9%,特异性为83.5%).
- 波形指数和疼痛值指数没有显示与ED有显著的关联.
结论:
- 由EEG波波分析得出的焦虑指数和舒适指数与儿科牙科手术患者的ED有关.
- 这些指数可以作为麻醉师识别和管理儿童ED的宝贵工具.
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