对阿片类药物使用障碍住院患者进行同行恢复教练干预:试点随机对照试验
Joji Suzuki1, Bianca Martin, Frank Loguidice
1From the Department of Psychiatry, Brigham and Women's Hospital, Boston, MA (JS, BM, FL); Harvard Medical School, Boston, MA (JS, JLS, RDW); Department of Psychiatry, University of Massachusetts Chan Medical School, Worcester, MA (DS); Division of General Internal Medicine, University of Pittsburgh, UPMC, Pittsburgh, PA (JML); Division of General Internal Medicine, Brigham and Women's Hospital, Boston MA (JLS); and McLean Hospital, Belmont, MA (RDW).
同行恢复教练干预并没有改善住院患者对阿片类药物使用障碍 (MOUDs) 的药物保留. 这项试点研究发现,在六个月后,治疗持续或再入院的情况没有显著差异.
科学领域:
- 成 药物 药物 药物 药物
- 心理社会干预 心理社会干预
- 临床试验 临床试验
背景情况:
- 阿片类药物使用障碍 (OUD) 患者面临高的住院率和出院后的治疗中止.
- 对阿片类药物使用障碍 (MOUDs) 的药物治疗至关重要,但保留仍然是一个挑战.
- 心理社会支持可以改善OUD患者的治疗坚持.
研究的目的:
- 评估同行恢复教练干预是否能提高住院OUD患者的MOUD治疗保留率.
- 评估恢复教练对复发预防和社区资源连接的影响.
- 为了比较干预和对照组之间的MOUD保留率和医院再入院.
主要方法:
- 试点随机对照试验比较同行恢复教练干预与通常治疗.
- 干预包括复发预防计划,MOUD鼓励和资源识别.
- 参与者被跟踪了6个月,结果包括MOUD保留和医院再入院.
主要成果:
- 在康复教练组 (38.5%) 和照常治疗组 (41.7%) 之间,在6个月的MOUD治疗保留期没有显著差异.
- 六个月后的再入院率相似:干预组的46.2%,对照组的41.2%.
- 治疗停止和再入院的时间在两组之间没有显著差异.
结论:
- 试点同行恢复教练干预并没有显著改善住院OUD患者的MOUD治疗保留率.
- 可能需要进一步的研究来探索替代或修改的心理社会干预措施.
- 目前的研究结果表明,在这种患者群体中,这种特定干预措施存在局限性.
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