最近开始办公室布普伦诺芬治疗的患者中非阿片类药物使用
Karen L Dugosh1, Michelle R Lent, S Brook Burkley
1From the Research and Evaluation Group, Public Health Management Corporation, Philadelphia, PA (KLD, SBB, CMKM); School of Professional and Applied Psychology, Philadelphia College of Osteopathic Medicine, Philadelphia, PA (MRL); Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (JRM, KMK).
Journal of addiction medicine
|October 3, 2023
概括
许多开始治疗阿片类药物使用障碍 (OUD) 的患者也使用其他物质,如大麻和可卡因. 这凸显了需要综合护理,解决非阿片类药物使用以及OUD治疗的需求.
科学领域:
- 成 药物 药物 药物 药物
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 治疗阿片类药物使用障碍 (MOUDs) 的药物,如布普伦诺芬,是治疗阿片类药物使用障碍 (OUD) 的主要治疗方法.
- MOUDs不是为了影响非阿片类药物的使用而设计的.
- 了解同时使用非阿片类药物对全面的OUD治疗至关重要.
研究的目的:
- 描述最近开始在办公室接受布普伦诺芬治疗OUD的患者的非阿片类药物使用模式.
- 提供当前关于该人口中同时出现的物质使用的数据.
主要方法:
- 一项描述性研究,利用来自两个正在进行的临床试验的数据.
- 包括来自中大西洋地区联邦合格卫生中心的257名患者.
- 基线评估包括尿液药物查和在28天内开始接受布普伦诺芬治疗的参与者的心理面试.
主要成果:
- 超过一半的参与者 (50%+) 的尿样呈非阿片类药物阳性.
- 大麻是最常被检测到的物质 (37%),其次是可卡因 (22%) 和二 (11%).
- 具体的流行率包括:大麻 (37%,n=95),可卡因 (22%,n=56),类药物 (11%,n=28).
结论:
- 许多开始接受布普伦诺芬治疗的患者继续使用非阿片类药物.
- 辅助心理社会治疗和支持可能对接受MOUD的OUD患者有益,他们也使用其他药物.
- 这强调了物质使用障碍的复杂性和需要多方面的治疗方法.
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