妊娠期热囊细胞疾病的手术管理
Leonoor Coopmans1, Agnes Larsson2, Ulrika Joneborg2
1Gynecological Oncology, Center for Gynecological Oncology Amsterdam, Netherlands Cancer Institute, Amsterdam, The Netherlands, l.coopmans@nki.nl.
Gynecologic and obstetric investigation
|October 3, 2023
概括
手术对于诊断和治疗妊娠 trofhoblastic 疾病 (GTD) 和妊娠 trofhoblastic 瘤 (GTN) 是至关重要的. 虽然化疗是有效的,但手术干预,如切和子宫切除仍然对患者治愈至关重要.
科学领域:
- 妇科 妇科医生 妇科
- 在瘤学瘤学.
- 生殖医学 生殖医学
背景情况:
- 孕期热囊细胞疾病 (GTD) 包含来自热囊细胞增殖的前恶性和恶性疾病.
- 恶性形式,孕期热囊细胞瘤瘤 (GTN),对化疗敏感,但通常需要手术治疗.
- 外科手术对于GTD的诊断和治疗是不可或缺的.
研究的目的:
- 审查GTD和GTN的手术干预措施.
- 总结手术治疗的指示,疗效,并发症和瘤学结果.
- 提供GTD/GTN.手术管理的最新概述.
主要方法:
- 在PubMed,Embase和Cochrane图书馆 (1952-2022) 的系统文献搜索.
- 专注于初级子宫切除术,第二次切除术,节育手术和转移性GTN管理.
- 包括英语,西班牙语和法语的文章.
主要成果:
- 吸管切割是GTD最常见的手术治疗方法.
- 第二次切割可能有利于低hCG和FIGO得分的患者.
- 由于GTN风险较低,初级子宫切除术是女性完成生育的选择.
- 手术切除是罕见GTN类型 (ETT,PSTT) 的关键.
- 由于数据有限,GTN的节育手术是实验性的.
结论:
- 手术是GTD和GTN治疗的重要组成部分,有时需要治疗.
- 需要进一步的研究来制定最终的手术治疗指南.
- 手术管理在实现最佳瘤治疗结果方面发挥着至关重要的作用.
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