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腰椎脊柱狭窄和轴性肌肉衰竭之间的关系

Lukas Schönnagel¹, Jiaqi Zhu², Gaston Camino-Willhuber³

¹Spine Care Institute, Hospital for Special Surgery, New York City, NY, USA; Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.

The spine journal : official journal of the North American Spine Society

|October 3, 2023

概括

腰椎脊柱狭窄症 (LSS) 与后侧副脊柱肌肉 (PPM) 中脂肪透的增加有关. 这种肌肉退化可能会使脊柱不稳定性恶化,在LSS患者中产生反循环.

科学领域:

脊柱成像和分析
肌肉骨研究的研究.
神经外科和整形外科的神经外科.

背景情况:

关于腰椎脊柱狭窄症 (LSS) 对后侧脊柱肌肉 (PPM) 的影响的研究有限.
在LSS中脊柱管道的压缩可能会影响PPM内置,可能导致缩和脂肪透 (FI).

研究的目的:

评估腰椎缩 (LSS) 与后侧脊柱肌肉缩 (PPM) 之间的关联.

主要方法:

522名患者的腰部核磁共振成像的回顾性分析,这些患者正在接受腰部疼痛或手术前检查的评估.
使用希萨斯分类来评估LSS,并测量了PPM功能横截面积 (fCSA) 和脂肪透 (FI) 在L4.4.
使用威尔科克森签名等级测试和多变量线性回归,调整年龄,性别,BMI和磁盘退化.

主要成果:

在任何腰部水平 (p<.001) 的狭窄时,观察到明显增加的PPM脂肪透 (FI).
多变量回归显示,L1/2,L2/3和L3/4的LSS与FI增加相关 (p=.013,p<.01,p=.003).
在L4/5的LSS严重程度与fCSA正相关 (p=.019).

结论:

在LSS和PPM组成之间存在显著的,独立的关联,根据狭窄水平而异.
脊髓硬化症患者可能会经历轴性肌肉衰竭,可能会加剧脊髓不稳定性,并创建一个积极的反循环.

关键词:

轴性肌肉缩轴性肌肉缩轴性肌肉缩退行性磁盘疾病是一种退行性磁盘疾病.椎间盘退化椎间盘退化腰椎脊柱狭窄症腰椎脊柱狭窄症腰椎脊柱的腰椎脊柱是指腰椎脊柱的部分.副脊柱肌肉是指脊柱肌肉中的一个.

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