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Updated: Jul 15, 2025

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在小鼠中对人类肺癌的途径向治疗的临床前建模

Aria Vaishnavi1, Conan G Kinsey1,2, Martin McMahon3,4,5

  • 1Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

Cold Spring Harbor perspectives in medicine
|October 3, 2023
PubMed
概括

基因工程小鼠模型 (GEMMs) 对于理解癌症发展和测试新疗法至关重要. 这些模型加速将临床前发现转化为有效的患者治疗,改善癌症护理.

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Mouse Models of Cancer Study02:43

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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