在COVID-19和没有COVID-19的患者之间,呼吸速率和氧和度之间的关系是否存在差异? 来自基于队列的相关性研究的见解
Mikael Laredo1,2, Claire Vandiedonck3, Òscar Miró4
1Réanimation Médicale et Toxicologique, Hôpital Lariboisière, APHP; INSERM UMRS-1144, Université de Paris, Paris, France.
Emergency medicine journal : EMJ
|October 3, 2023
概括
在COVID-19患者的呼吸速率和氧和度之间的关系与非COVID-19患者相似,除了80岁以上的患者. 在COVID-19患者中,沉默性低氧化症并不比较频繁.
科学领域:
- 紧急医疗 紧急医疗
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19呈现出"无声低氧症",这是一个有争议的现象,患者在没有呼吸困扰的情况下氧和率低.
- 了解呼吸速率 (RR) 和外周氧和 (SpO2) 之间的关系对于患者的评估至关重要.
研究的目的:
- 为了比较RR/SpO2关系在COVID-19与非COVID-19患者在入院时.
- 在这些患者群体中确定与"无声低氧化症"相关的因素.
主要方法:
- 对COVID-19和下呼吸道细菌感染患者的回顾性多中心队列研究.
- 多变量线性和逻辑回归模型用于分析RR,SpO2和"静音低氧症".
主要成果:
- 与非COVID-19患者相比,COVID-19患者在入院时的RR较低,SPO2较高.
- 在80岁及以上的COVID-19患者中,RR/SpO2相关性不同.
- "无声低氧症" (RR <20/分钟,SpO2 <95%) 在14.8%的COVID-19患者和16.6%的非COVID-19患者中观察到,与年龄≥80.0相关.
结论:
- 在COVID-19和非COVID-19患者中,RR/SpO2的关系类似,在老年人中有显著的例外.
- 年龄是"无声低氧化症"的一个重要因素,无论COVID-19状态如何.
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