长期COVID需要多长时间? 在前性队列研究中,12至18个月间的症状改善
Robert M Barker-Davies1,2, O O'Sullivan1,3, D A Holdsworth4,5
1Academic Department of Military Rehabilitation, Defence Medical Rehabilitation Centre, Loughborough, UK.
BMJ military health
|October 3, 2023
概括
COVID-19幸存者经历了抑郁症,疲劳和运动能力降低长达12个月. 与对照组相比,这些长期COVID症状在感染后的18个月内显著改善.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 传染病 传染病 传染病
背景情况:
- COVID-19可能导致长期的感染后综合征.
- 症状包括疲劳,运动不耐受,以及认知/情绪障碍.
研究的目的:
- 为了比较COVID-19中疲劳,运动,情绪和认知结果,暴露个体与对照对照.
- 随着时间的推移来表征长期COVID症状.
主要方法:
- 对113名英国武装部队参与者的前性队列研究进行了18个月的跟踪.
- 评估COVID-19暴露 (n=56) 和匹配的对照 (n=14) 在5,12和18个月.
- 使用了症状检查清单,PROM (FAS,GAD-7,PHQ-9,PCL-5),认知测试和6分钟步行测试 (6MWT).
主要成果:
- 暴露的参与者在5个月和12个月后显示出更高的抑郁症 (PHQ-9),PTSD (PCL-5) 和疲劳 (FAS) 评分.
- 暴露个体在5个月和12个月后的运动表现 (6MWT) 显著下降.
- 在任何时间点,认知功能和焦虑 (GAD-7) 在各组之间没有显著差异.
结论:
- 在COVID-19后12个月观察到抑郁症,PTSD,疲劳和运动表现的不良结果.
- 这些症状在18个月的随访后有所改善.
- 这些发现突出了长期COVID症状解决的时间性质.
相关概念视频
Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
Longitudinal Studies
186
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
186
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
COPD: Pathogenesis and Clinical Features
327
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
327
Classification of Illness
7.6K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
7.6K
Stages of Infection
56.8K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
56.8K


