从埃及发酵食品中分离出来的乳酸细菌的益生菌潜力
Fatma I Abdel Tawab1, Menna H Abd Elkadr2, Amany M Sultan3
1Oil Crops Biotechnology Lab, Agricultural Genetic Engineering Institute, Agricultural Research Center, Giza, Egypt.
Scientific reports
|October 3, 2023
概括
研究人员从埃及发酵食品中发现了四种安全的乳酸细菌 (LAB) 菌株,这些菌株具有益生菌潜力. 这些菌株表现出抗微生物,抗氧化剂和抗癌作用,有利于人类和动物的健康.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 益生菌 益生菌 益生菌
背景情况:
- 发酵食品中的乳酸细菌 (LAB) 提供健康益处和益生菌性质.
- 识别和评估新的益生菌对全球健康和经济至关重要.
- 埃及发酵食品是新型益生菌菌株的潜在来源.
研究的目的:
- 从埃及发酵食品中分离和功能性地鉴定LAB菌株的益生菌潜力.
- 为了评估这些LAB菌株的安全性和有效性,在体外和体内.
- 为了确定具有抗微生物,抗氧化剂和抗癌活性的特定菌株.
主要方法:
- 从埃及发酵食品中分离和描述100种细菌菌株.
- 在体外评估益生菌属性,抗菌活性和抗氧化能力.
- 在小鼠体内安全性和疗效评估,包括生长性能和抗氧化剂水平.
- 对Caco-2结肠癌细胞系进行了抗癌效应测试.
主要成果:
- 四种LAB菌株表现出显著的益生菌属性和安全性,可作为补充剂使用.
- 在IS06中,Enterococcus massiliensis显示出高的抗微生物,抗氧化剂和抗结肠癌活性.
- 在体内研究证实了大鼠补充剂的安全性,其中Lactiplantibacillus plantarum IS07增强了生长.
- 这四种菌株都增加了体内抗氧化剂水平 (超氧化脱酶,谷氨) 和体内抗氧化剂活性.
结论:
- 孤立的LAB菌株具有人类和动物应用所需的益生菌特性.
- 这些益生菌可以作为有效的料添加剂和食补充剂.
- 已识别的菌株在打击严重疾病和促进整体健康方面具有潜力.
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