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移植后的初级双边结核性中耳炎:一个病例报告
Jeon Mi Lee1, Keun-Woo Jung1, Ki-Won Kim1
1Department of Otorhinolaryngology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
The journal of international advanced otology
|October 4, 2023
概括
这项研究详细介绍了一例罕见的初级双侧结核性中耳炎病例,该病例发生在免疫受损患者身上. 不寻常的呈现和组织病理学突出显示了这种肺外结核疾病表现的新临床变异.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 结核性中耳炎是一种罕见的肺外结核病.
- 免疫抑制,如移植后的免疫抑制,可以增加对感染的易感性.
- 传统的结核性耳中炎通常具有特定的临床和组织病理特征.
研究的目的:
- 报告一种单一的初级双边结核性中耳炎病例.
- 描述这个患者的不寻常的临床和组织病理学发现.
- 为了突出结核性中耳炎的新型临床变异.
主要方法:
- 一个75岁的女性移植接受者的病例报告.
- 临床检查,耳镜检查和成像研究.
- 手术干预后进行了他的病理学检查,齐尔-尼尔森染色和聚合酶链反应 (PCR).
主要成果:
- 患者呈现双边性耳部泄漏和听力损失,对抗生素无反应.
- 组织病理学揭示了具有兰根斯巨细胞的多焦点颗粒瘤,缺乏病变变化.
- 齐尔-尼尔森染色和PCR证实了结核性中耳炎作为主要感染.
结论:
- 这种病例代表了一次性,双侧结核性中耳炎,具有非典型的临床和病理学特征.
- 这些发现扩大了已知的结核性中耳炎的范围,特别是在免疫受损的个体中.
- 这种呈现表明这种罕见的肺外结核病的新临床变异.
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