TFE3重组细胞癌的病例报告:FDG-PET摄入可能有助于诊断
Sho Murakami1, Keita Nagawa1, Takanori Inui1
1Department of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
转位和转录因子E3 (TFE3) 重组的细胞癌 (RCC) 很罕见,难以诊断. 在用CT (FDG PET-CT) 标记-18的氧糖正子发射断层扫描上,高标准化吸收值 (SUVmax) 可能表明TFE3重组RCC的高恶性潜力.
科学领域:
- 在瘤学瘤学.
- 分子生物学分子生物学
- 医疗成像医学成像
背景情况:
- TFE3重组细胞癌 (RCC) 是一种罕见的儿童和成人恶性瘤.
- 由于CT/MRI上与其他RCC亚型重叠的成像特征,诊断具有挑战性.
研究的目的:
- 使用FDG PET-CT.报告TFE3重排的RCC的成像特征.
- 研究FDG PET-CT在评估TFE3重组RCC的恶性潜力的潜力.
主要方法:
- 对TFE3重组RCC患者的病例报告分析.
- 评估FDG PET-CT成像特征,包括标准化吸收值 (SUVmax).
主要成果:
- 在初级瘤 (7.14和6.25) 中,FDG PET-CT 显示了高标准化吸收值 (SUVmax).
- 高SUVmax表明TFE3重组RCC的高恶性潜力.
- 这些发现与已知的疾病分子背景和葡萄糖代谢相关.
结论:
- 在FDG PET-CT上高SUVmax可能是TFE3重排的RCC的临床特征.
- FDG PET-CT可以为这种罕见的脏恶性瘤的攻击性提供宝贵的见解.
更多相关视频
10:28Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
06:51Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
Published on: July 21, 2018
相关概念视频
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies III: Computed Tomography
