药理学活动和Ganoderma lucidum子的安全性:一个系统的审查
Nguyen Huu Lac Thuy1, Vo Linh Tu2, Le Nguyen Anh Thu1
1Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, VNM.
Cureus
|October 4, 2023
概括
子提取物显示出显著的抗瘤,抗炎,抗氧化和免疫调节作用,类似于本身. 破坏了子的子.
科学领域:
- 药理学和传统医学的医学.
背景情况:
- 传统上Ganoderma lucidum用于各种健康状况,包括肝脏疾病,高血压,失眠,糖尿病和癌症.
- 胞提取物Ganoderma lucidum被认为具有与的其他部分提取物相比较的生物活性.
研究的目的:
- 系统地审查和总结有关Ganoderma lucidum子提取物的药理作用和安全性的现有证据.
- 澄清Ganoderma lucidum子提取物对未来研究和治疗策略的潜在应用的益处.
主要方法:
- 2021年9月13日,在五个主要数据库 (PubMed,VHL,GHL,SIGLE,Google Scholar) 进行了全面的文献搜索.
- 应用了包含和排除标准,并通过手动搜索来确定相关研究.
- 系统性审查包括了90项研究,详细介绍了Ganoderma lucidum子的药理作用和/或安全性.
主要成果:
- 的子提取物具有与的其他部分相似的药理作用,包括抗瘤,抗炎,抗氧化和免疫调节活动.
- 与未破碎的子提取物相比,Ganoderma lucidum子提取物表现出更高的疗效.
- 提取物影响了参与新陈代谢的基因,这表明对代谢疾病的潜在益处.
- 高剂量的Ganoderma lucidum提取物可能会增加癌症抗原 (CA) 72-4水平,尽管没有观察到器官毒性,但需要谨慎.
结论:
- 光的子提取物具有预防和治疗疾病的显著药理潜力.
- 运动皮破裂技术提高了提取物的有效性,为开发更有效的治疗剂提供了有希望的途径.
- 由于CA72-4.4的潜在增加,建议进一步调查高剂量Ganoderma lucidum子提取物的安全性.
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