在患有严重COVID-19肺炎的患者中分析多个器官功能损伤
Shiyan Feng1, Fengxin Wang1, Weibo Wu1
1Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People's Hospital, Shenzhen, Guangdong Province, China.
Journal of medical biochemistry
|October 4, 2023
概括
器官功能测试揭示了严重和轻度的冠状病毒疾病2019 (COVID-19) 肺炎患者之间的显著差异. 这些发现有助于预测器官损伤,并指导COVID-19治疗策略.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 临床生物化学 临床生物化学
背景情况:
- 严重的冠状病毒疾病2019 (COVID-19) 肺炎造成器官损伤的重大风险.
- 了解器官功能变化对于管理严重的COVID-19病例至关重要.
研究的目的:
- 分析严重的COVID-19肺炎中器官功能指数的变化和意义.
- 预测主要器官损伤并指导COVID-19患者的治疗方案.
主要方法:
- 在重症 (n=63) 和轻症 (n=73) COVID-19组之间对器官功能指数的比较分析.
- 使用SAS9.4软件进行统计分析.
- 将定量变量转换为分析的分类变量.
主要成果:
- 与温和组相比,严重的COVID-19组显示ALT,AST,cTnI,Cr,PT,APTT和D-二次体的水平显著更高.
- 在严重的COVID-19组中,血小板 (PLT) 数量显著下降.
- 在重症组中发现了较高的AST,ALB,D-二次体水平和双边肺部干扰.
结论:
- 在重度和轻度的COVID-19肺炎之间存在多个器官功能指数的显著差异.
- 器官功能指数可以预测COVID-19患者的多器官损伤.
- 这些预测可以为COVID-19的临床治疗策略提供信息和指导.
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