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Updated: Jun 25, 2026

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在SYNGAP1突变的临床前模型中,过度兴奋性和转化表型

Jill L Silverman1, Timothy Fenton2, Olivia Haouchine

  • 1MIND Institute and Department of Psychiatry and Behavioral Sciences, University of California Davis School of Medicine.

Research square
|October 4, 2023
PubMed
概括

具有SYNGAP1突变的小鼠表现出显著的睡眠障碍,包括大脑波活动和神经元发射模式的改变. 这些发现在临床试验中确定了SYNGAP1相关智力障碍 (SYNGAP1-R-ID) 的潜在生物标志物.

关键词:
这就是 Syngap1 的原因.行为行为行为行为.认知 认知 认知微电极阵列是一个微电极阵列.鼠标模型 鼠标模型鼠标模型神经发育障碍是一种神经发育障碍.生理学 生理学 生理学睡眠 睡眠 睡眠 睡眠 睡眠

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