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男性和女性前脑电路的激活模式在新奇的食物消费期间
Eliza M Greiner1, Mary E Witt1, Stephanie J Moran1
1Boston College.
Research square
|October 4, 2023
概括
食物或环境中的新奇性通过改变神经活动显著影响养行为. 不同的大脑区域被新鲜的食物和新鲜的环境激活,观察到基于性别的差异.
科学领域:
- 神经科学是一个神经科学.
- 行为神经科学 行为神经科学
- 神经生物学 神经生物学 神经生物学
背景情况:
- 新奇影响养行为,可能会因为感知到的危险而取代平静和快乐的驱动.
- 以前的研究表明,新型食物缺食在新型环境中被放大,男性比女性更快地习惯.
研究的目的:
- 研究不同的神经机制,这些神经机制是食品新性和环境新性对养行为的影响的基础.
- 为了确定由新食物与新环境激活的特定大脑区域.
主要方法:
- 成年雄性和雌性老鼠在熟悉或新鲜的环境中消耗了新鲜或熟悉的食物.
- 测量神经激活的标记物Fos表达,测量了参与食欲,上下文处理和奖励的关键大脑区域.
主要成果:
- 新的背景诱导了广泛的Fos表达在杏仁体,thalamus,条纹体和前额叶皮层.
- 新鲜的食物在更具体的区域触发了Fos表达,包括杏仁体,乳腺体和岛内皮层.
- 观察到神经激活的性别差异,男性在某些杏仁体中表现出更多的激活,而女性在乳头和核中表现出更多的激活.
结论:
- 食物的新奇性和背景的新奇性激活了不同的神经回路.
- 这些发现表明,独立的功能电路控制了由食物本身的新性和环境的新性影响的养行为.
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