相关实验视频
Updated: Jul 15, 2025

08:38
Extraction and Analysis of Cortisol from Human and Monkey Hair
Published on: January 24, 2014
28.4K
预先怀孕和怀孕的相关因子 头发皮质醇度 皮质醇度
Diana L Juvinao-Quintero1, Richard G Künzel1, Gloria Larabure-Torrealva2
1Department of Epidemiology, Harvard T.H. Chan School of Public Health.
Research square
|October 4, 2023
概括
怀孕前的体重指数 (BMI) 和抑郁症是影响怀孕期间头发皮质醇度 (HCCs) 的关键因素. 了解这些慢性压力生物标志物对于改善母亲和婴儿健康结果至关重要.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 心理神经免疫学 心理神经免疫学
背景情况:
- 怀孕期间的慢性压力可能会对母亲和胎儿的健康产生负面影响.
- 头发皮质醇度 (HCC) 是长期皮质醇暴露的可靠生物标志物.
- 在怀孕前和怀孕期间确定影响HCC的因素对于有针对性的干预至关重要.
研究的目的:
- 在怀孕前和怀孕期间调查头发皮质醇度 (HCC) 的相关值.
- 确定与孕妇HCC相关的社会人口结构,生活方式和心理社会因素.
主要方法:
- 分析了2581名孕妇在四个产前期使用LC-MS/MS的HCC.
- 评估社会人口统计学,与怀孕有关的,与头发有关的和心理社会压力因素.
- 统计分析包括斯皮尔曼相关性,t测试,ANOVA和多变量线性回归.
主要成果:
- 在产前期间,HCC平均水平显著增加 (P < 0.001).
- 在怀孕前的BMI显示出在整个怀孕期间与HCC的一致关联.
- 怀孕年龄,经济困难,染发和抑郁症与HCC的时间特定关联.
结论:
- 几个因素影响妊娠前和妊娠期间的HCC水平,怀孕前的BMI是最一致的相关因素.
- 抑郁症也与HCC度有显著的关联,突出显示了心理健康和生理压力之间的相互作用.
- 这些发现强调了监测和管理BMI和心理健康等因素的重要性,以减轻怀孕期间的慢性压力.
相关概念视频
Hypothalamic-Pituitary Axis
60.4K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
60.4K
Hormones of the Adrenal Glands
2.5K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
2.5K
Correlations
32.9K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
32.9K
Correlation and Causation
37.7K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
37.7K
Accessory Structures of the Skin: Hair Growth and Types
1.4K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
1.4K
Gonadal and Placental Hormones
1.5K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
1.5K

