相关实验视频
Updated: Jul 15, 2025

09:43
Methods to Test Endocrine Disruption in Drosophila melanogaster
Published on: July 3, 2019
9.8K
COVID-19对内分泌系统的长期影响 - 一项试点病例控制研究
Łukasz Szczerbiński1,2,3,4, Michał Andrzej Okruszko1,5, Maciej Szabłowski1
1Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland.
Frontiers in endocrinology
|October 4, 2023
概括
在COVID-19感染六个月后,幸存者表现出持久的内分泌系统影响,包括改变甲状腺功能和男性较低的丸激素. 血糖和身体成分保持不变.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病2019 (COVID-19) 的长期内分泌并发症在很大程度上是未知的.
- 这项研究调查了严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染在感染后六个月内分泌系统的持续影响.
研究的目的:
- 评估COVID-19在最初感染后六个月内分泌和代谢参数的影响.
- 为了比较COVID-19幸存者的内分泌和代谢资料与大流行前的对照.
主要方法:
- 将COVID-19患者与年龄和性别匹配的对照进行比较,这些对照来自于一项大流行前的人口研究.
- 评估了禁食葡萄糖,胰岛素,脂质,身体组成,甲状腺激素 (TSH,ft4,ft3),甲状腺抗体 (aTG,aTPO),前素,皮质醇,和雌激素.
主要成果:
- COVID-19幸存者表现出较低的自由三甲状腺素 (fT3) 和自由甲状腺素 (fT4),较高的甲状腺刺激激素 (TSH) 和较高的抗甲状腺过氧化酶 (aTPO) 抗体.
- 在COVID-19患者中观察到血清素升高和丸激素降低;丸激素降低是男性特有的.
- 没有注意到身体组成或血糖参数的显著差异,除了幸存者的HOMA2-B指数更高.
结论:
- 感染SARS-CoV-2可以导致长期内分泌功能障碍,影响甲状腺功能,前素和男性性激素分泌.
- 六个月的随访显示,COVID-19对血糖参数,脂质概况,肝功能,身体组成,皮质醇或雌激醇没有显著影响.
相关概念视频
The Endocrine System
329
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
329
An Overview of the Endocrine System
8.5K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
The endocrine system collaborates...
8.5K
What is the Endocrine System?
414.6K
The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
414.6K
Major Hormones and Their Functions
473
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
473
Structures of the Endocrine System
7.7K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
7.7K
Psychoneuroimmunology: Diabetes and Cancer
44
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
44

