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Updated: Jul 15, 2025

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在塞浦路斯乳腺癌病例和对照中进行多基因小组测试和关联分析

Maria Zanti1, Maria A Loizidou2, Denise G O'Mahony1

  • 1Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

Frontiers in genetics
|October 4, 2023
PubMed
概括

这项研究揭示了塞浦路斯与乳腺癌有关的遗传变异的流行程度. 它确定了与乳腺癌风险增加相关的特定基因,为遗传检测和患者护理提供了关键的见解.

关键词:
在MASTOS研究中,MASTOS研究的结果是:乳腺癌的易感性 乳腺癌的易感性案例控制 - 案例控制这是下一代测序.面板测序的排序方式

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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