长期预后和预测患者的死亡率在经过过导管大动脉置换的患者:回顾性分析
Harshitha Thogata1, Sushmitha Garikipati2, Shanthi Reddy S3
1Department of General Medicine, Narayana Medical College and Hospital, Nellore, IND.
Cureus
|October 4, 2023
概括
超导管大动脉置换 (TAVR) 显示73.5%的生存率,但年龄,男性性别,冠状动脉疾病 (CAD),糖尿病 (DM) 和慢性病 (CKD) 增加死亡风险. 个性化管理是TAVR患者的关键.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 老年医学 老年医学
背景情况:
- 大动脉膜疾病带来了重大的健康挑战和死亡风险.
- 过导管大动脉置换 (TAVR) 是一种革命性的微创治疗方法.
- 长期TAVR结果和患者适应性需要继续调查.
研究的目的:
- 分析500名接受TAVR的患者的长期结果.
- 为了确定TAVR程序后死亡率的预测因素.
- 评估TAVR后的生存率和主要不良心脏事件 (MACE).
主要方法:
- 从2020年1月到2023年7月对500名TAVR患者的回顾性分析.
- 收集人口统计数据,并发症和TAVR结果.
- 考克斯比例危险回归用于确定死亡率预测因素.
主要成果:
- 研究队列的平均寿命为75.6年,患有高血压 (74%) 和CAD (68%) 等常见的并发症.
- 总体长期生存率为73.5%,随访时间中位数为5.2年.
- 死亡率预测因素包括较高的年龄,男性性别,CAD,糖尿病 (DM) 和慢性病 (CKD) 阶段≥3.
结论:
- 年龄,男性性别,CAD,DM和晚期CKD是TAVR后的显著死亡风险因素.
- 之前的冠状动脉旁路移植 (CABG) 与降低死亡风险有关.
- 风险分层和个性化管理对于优化TAVR结果至关重要.
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