Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

411
Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
The ATR process begins by directing a beam...
411
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

439
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
439
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

449
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
449
IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration01:16

IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration

1.4K
A covalently bonded heteronuclear diatomic molecule can be modeled as two vibrating masses connected by a spring. The vibrational frequency of the bond can be expressed using an equation derived from Hooke's law, which describes how the force applied to stretch or compress a spring is proportional to the displacement of the spring. In this case, the atoms behave like masses, and the bond acts like a spring.
According to Hooke's law, the vibrational frequency is directly proportional to...
1.4K
IR Spectrometers01:25

IR Spectrometers

1.2K
There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...
1.2K
Infrared (IR) Spectroscopy: Overview01:09

Infrared (IR) Spectroscopy: Overview

1.9K
When electromagnetic radiation passes through a material, atoms or molecules transition from a lower to a higher energy state by absorbing radiation corresponding to the energy difference between the two states. The absorption of infrared (IR) radiation causes transitions between vibrational energy levels in a molecule. Therefore, IR spectroscopy is a useful analytical tool for determining the molecular structure of molecules.
Different compounds display unique properties due to their...
1.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Can diffuse reflectance spectroscopy identify shuntodynia in pediatric hydrocephalus patients?

Journal of biomedical optics·2024
Same author

Numerical approach to quantify depth-dependent blood flow changes in real-time using the diffusion equation with continuous-wave and time-domain diffuse correlation spectroscopy.

Biomedical optics express·2023
Same author

Reconstruction of optical coefficients in turbid media using time-resolved reflectance and calibration-free instrument response functions.

Biomedical optics express·2022
Same author

Direct estimation of the reduced scattering coefficient from experimentally measured time-resolved reflectance via Monte Carlo based lookup tables.

Biomedical optics express·2020
Same author

The Histone Demethylase NO66 Induces Glioma Cell Proliferation.

Anticancer research·2019
Same author

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.

Nature communications·2019
Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026
Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026
Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026
Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026
Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026
Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026
查看所有相关文章

相关实验视频

Updated: Jul 15, 2025

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

12.5K

基于神经网络的反向模型用于扩散反射光谱学.

Qing Lan1,2, Ryan G McClarren1,3, Karthik Vishwanath4,5

  • 1Department of Aerospace and Mechanical Engineering, University of Notre Dame, Indiana, USA.

Biomedical optics express
|October 4, 2023
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种新的神经网络方法,可以从分散反射光谱数据中快速准确地确定光学特性. 这种方法为潜在的临床诊断提供了比传统方法更快的替代方案.

更多相关视频

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

7.9K
Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging
07:06

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

7.7K

相关实验视频

Last Updated: Jul 15, 2025

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

12.5K
Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

7.9K
Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging
07:06

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

7.7K

科学领域:

  • 生物医学光学 生物医学光学
  • 计算成像技术的成像
  • 频谱学是一种光谱学.

背景情况:

  • 分散反射光谱 (DRS) 对于非侵入性地测量组织光学特性至关重要.
  • 目前的方法依赖于计算密集的前模型 (例如,蒙特卡洛模拟) 进行反向问题解决.
  • 准确的光学属性检索对于临床诊断等应用至关重要.

研究的目的:

  • 开发和验证一种基于神经网络的新型反向模型,用于扩散反射光谱.
  • 用实验数据评估神经网络模型与传统方法的性能.
  • 探索神经网络在DRS中加速光学属性检索的潜力.

主要方法:

  • 使用蒙特卡洛模拟数据预训练了一个神经网络前置模型.
  • 训练的前向模型被用来创建用于反转反射频谱的查找表.
  • 基于神经网络的反向模型是通过从光学幻影获得的实验获得的分散反射率数据来构建和测试的.

主要成果:

  • 基于神经网络的反向模型从实验数据中准确地检索了光学特性.
  • 该模型的准确性与传统的基于蒙特卡洛的反向模型相比较.
  • 与传统方法相比,观察到速度和灵活性的显著改善.

结论:

  • 神经网络提供了一种有希望和有效的方法来解决分散反射光谱学的反向问题.
  • 开发的模型为光学属性检索提供了一个可行的,更快的替代方案,可能会推进临床诊断工具.
  • 这项研究强调了机器学习在增强光谱分析和生物医学成像方面的潜力.