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重要性采样-加速模拟全频谱反射分散的分散反射

Jianing Mao¹, Yuye Ling¹, Ping Xue²

¹Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

Biomedical optics express

|October 4, 2023

概括

我们开发了一种重要的采样方法,以加速全频谱反射分散反射 (F-BDR) 的蒙特卡洛模拟. 这种技术可显著加快光-组织相互作用建模,用于诸如光学相干断层扫描等应用.

科学领域:

生物医学光学生物医学光学
计算物理计算物理
医疗成像医学成像

背景情况:

蒙特卡洛 (MC) 模拟对于建模光组织相互作用至关重要,但对于全频谱反射分散反射 (F-BDR) 则计算密集.
低光子采集效率和模拟整个发射频谱有助于F-BDR传统MC方法的高计算成本.

研究的目的:

使用重要性抽样 (IS) 开发一个模拟F-BDR的加速方案.
为了提高MC模拟的计算效率,用于光-组织相互作用建模.

主要方法:

推导出用于BDR模拟的偏差采样函数,使用两项 (TT) 散射相函数,配备Mie散射.
将TT函数及其偏差函数纳入重新定义的IS过程,以加速F-BDR模拟.
通过使用虚拟模拟与福里埃域光学连贯断层扫描 (FD-OCT) 验证了该方法.

主要成果:

与原来的MC模拟器相比,在F-BDR模拟中实现了多层幻影的373×加速.
保持较低的相对平均平方误差 (rMSE) 低于2%.
通过并行A线计算,能够在0.4小时内模拟一个复杂幻影的整个体积OCT图像.

结论:

拟议的IS方法显著加速F-BDR模拟,使其成为各种生物医学光学应用的宝贵工具.
这是首次报告复杂幻影体积OCT图像的模拟.
方法的效率和准确性得到证明,源代码的可用性促进了进一步的研究和应用.

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