老年人血清维生素D状态:一个队列研究
Simin Mouodi1, Sajedeh Delbari1, Seyed Reza Hosseini1
1Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Iranian journal of medical sciences
|October 4, 2023
概括
在5年内,老年人血清维生素D水平显著下降. 维生素D和补充剂,以及副甲状腺激素,和水平,影响了这种下降.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 维生素D对骨代谢和维持和酸盐平衡至关重要.
- 随着时间的推移,血清维生素D度的变化对老年人健康很重要.
- 这项研究调查了影响老年人维生素D水平的因素.
研究的目的:
- 评估老年人血清维生素D度的五年变化.
- 在这个人口群体中确定影响血清维生素D水平的因素.
- 了解补充剂和生物化学标记物对维生素D状态的影响.
主要方法:
- 在伊朗北部,对60岁及以上的成年人进行了一项为期五年的队列研究.
- 血清25-基维生素D (25-OH维生素D) 水平在基线和随访时被测量.
- 统计分析包括千平方,t测试,ANOVA和Tukey HSD后期测试.
主要成果:
- 平均血清25-OH维生素D度在五年内从34.68±33.18 ng/mL显著下降到23.88±14.91 ng/mL.
- 在随访时,维生素D缺乏,不足和充足分别在44.7%,33.0%和22.3%的参与者中观察到.
- 血清25-OH维生素D的减少与维生素D和补充剂以及副甲状腺激素,和的血清水平显著相关.
结论:
- 在老年人中,血清维生素D度在五年内下降,不论年龄,性别,BMI,代谢综合征或体力活动.
- 补充剂和特定的生物化学标记在调节老年人维生素D水平方面发挥着重要作用.
- 需要进一步的研究来阐明影响老年人群维生素D状况的因素的复杂相互作用.
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