高温增加了蜜蜂肠道共生体对寄生虫的抑制
Evan C Palmer-Young1, Lindsey M Markowitz1,2, Wei-Fone Huang1
1USDA-ARS Bee Research Lab , Beltsville, Maryland, USA.
Applied and environmental microbiology
|October 4, 2023
概括
蜜蜂肠道共生体,如乳杆菌,表现出更高的耐热性,并在更高的温度下产生更多的酸. 这提高了它们抑制寄生虫生长的能力,这表明温度影响了微生物组介导的抗感染能力.
科学领域:
- 微生物生态学 微生物生态学
- 动物共生是动物的共生.
- 主体-寄生虫相互作用
- 动物体内的温度调节
背景情况:
- 主体体温和肠道微生物群影响动物对寄生虫感染的抵抗力.
- 温度对肠道共生体抗寄生活动的影响仍然未得到充分研究.
- 蜜蜂肠道微生物群富含乳酸菌,经历温度波动影响宿主生理和寄生虫易感性.
研究的目的:
- 为了研究温度如何影响蜜蜂Lactobacillus共生体和试虫肠道寄生虫之间的相互作用.
- 为了确定温度是否调节蜂蜜中肠道共生体的抗寄生虫疗效.
主要方法:
- 在实验室中使用了乳杆菌共生体和蜜蜂试类寄生虫的细胞培养物.
- 对象和寄生虫的生长,耐热性和酸性生产在一系列温度范围内进行了测量.
- 对象的抗寄生虫活性在与蜜蜂群体相关的不同温度下进行了评估.
主要成果:
- 乳杆菌共生体表现出比寄生虫更大的耐热性,并通过酸生产抑制了寄生虫的生长.
- 蜜蜂殖民地范围内的温度升高放大了共生体的生长和酸的产生,从而产生了更强大的抗寄生虫效应.
- 共生体的存在降低了寄生虫的峰值生长率和耐热性,特别是在高温下.
结论:
- 温度显著改变了蜜蜂肠道共生体和寄生虫之间的相互作用,增强了微生物组介导的耐药性.
- 蜜蜂的内热能力可能会增强它们的肠道微生物群对感染的保护作用.
- 肠道微生物群功能的温度驱动调节是一种潜在的低估的机制,影响宿主对寄生虫的易感性.
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